5-Amino-1MQ

5-Amino-1MQ is a small molecule NNMT (nicotinamide N-methyltransferase) inhibitor that enhances cellular NAD+ levels and mitochondrial function. Originally developed for metabolic research, it's gaining attention for its potential anti-aging properties and ability to improve energy metabolism at the cellular level.

• NAD+ Enhancement
• Mitochondrial Function
• Cellular Repair

Enhanced NAD+ levels, improved mitochondrial function, longevity benefits, better energy metabolism, enhanced cellular repair, improved insulin sensitivity, convenient daily dosing

Orally administered 5-Amino-1MQ inhibits NNMT enzyme systemically, preventing NAD+ degradation and maintaining higher cellular NAD+ levels throughout the body, supporting mitochondrial function and metabolic processes

Peak plasma concentration: 48 min. Elimination half-life: 8 hrs. Largely cleared by: ~1.7 days.

Research protocols from published literature — not dosing recommendations.

• NAD+ Precursors (NMN, NR) — Synergistic: May work synergistically with NAD+ precursors by preventing breakdown while supporting production
• Resveratrol — Synergistic: Both support longevity pathways; resveratrol activates sirtuins while 5-Amino-1MQ provides NAD+ substrate
• Metformin — Monitor Combination: Both affect metabolic pathways; combination may enhance effects but requires careful monitoring
• BPC-157 — Compatible: No known interactions; different mechanisms of action with potential complementary benefits
• Blood Thinners — Unknown: Limited interaction data; consult healthcare provider before combining with anticoagulants
• Berberine — Monitor Combination: Both affect metabolic pathways; potential additive effects on glucose metabolism

Week 1-2: Gradual increase in energy levels and mental clarity. Week 2-4: Enhanced exercise performance and recovery. Week 4-8: Improved metabolic markers and body composition. Week 8-12: Sustained longevity benefits and cellular health. Side effects: Generally minimal, occasional mild GI adjustment. Most effective for: Metabolic health, longevity, energy enhancement.

No human clinical trials published - all dosing extrapolated from animal studies. 38.4% oral bioavailability demonstrated in rats (PubMed 34304009). Start with lowest effective dose (25-50mg) to assess tolerance. Take with food to reduce potential GI effects. Monitor for any unusual symptoms and discontinue if adverse effects occur. Not recommended for pregnant or breastfeeding women. Consult healthcare provider before use, especially with existing conditions.

No human clinical trials published - all dosing extrapolated from animal studies. 38.4% oral bioavailability demonstrated in rats (PubMed 34304009). Start with lowest effective dose (25-50mg) to assess tolerance. Take with food to reduce potential GI effects. Monitor for any unusual symptoms and discontinue if adverse effects occur. Not recommended for pregnant or breastfeeding women. Consult healthcare provider before use, especially with existing conditions.

5-Amino-1MQ should be stored at Cool, dry place at room temperature.